Preliminary Effect for Serum Albumin Level Evaluating the Patients With Chronic Heart Failure Treated by Cardiac Resynchronization
10.3969/j.issn.1000-3614.2015.04.010
- VernacularTitle:血清白蛋白水平评价慢性心力衰竭患者心脏再同步化治疗的初步探讨
- Author:
Xingtong ZHANG
;
Juan ZHAO
;
Miao WANG
- Publication Type:Journal Article
- Keywords:
Cardiac resynchronization;
Chronic heart failure;
Serum albumin;
Left ventricular ejection fraction;
Left ventricular end-diastolic dimension
- From:
Chinese Circulation Journal
2015;(4):343-345
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the preliminary effect for serum albumin (ALB) level in patients with chronic heart failure (CHF) treated by cardiac resynchronization (CRT).
Methods: A total of 54 CHF patients treated in our hospital from 2009-01 to 2013-12 were studied. The patients were divided into 2 groups: CRT group and Control group, in which the patients were treated by medication. n=27 in each group. The blood test of biochemistry, 24 hour dynamic ECG monitoring with QRS duration, echocardiography, ALB level, heart rate (HR), left ventricular end-diastolic dimension (LVEDD) and left ventricular ejection fraction (LVEF) were recorded at admission as baseline information, and the above examinations were repeated 2 to 3 times during 6-15 months of follow-up period.
Results: The age, gender and baseline information were similar between 2 groups. Compared with admission, during followed-up period, CRT group had increased ALB, LVEF, P<0.05, decreased HR, P<0.001, shorter QRS duration, P<0.001 and LVED remained similar;while Control group had decreased ALB, P<0.05 and LVEF, LVED, QRS duration, HR remained similar. Logistic regression analysis indicated that in CRT group, with adjusted LVEF, QRS duration and ALB, serum ALB level was the most relevant indicator for CRT efifcacy, P<0.01.
Conclusion: CRT could improve the cardiac function and increase ALB in CHF patients, therefore serum ALB level might be related to CRT efifcacy at certain degree.
