Differentiation of malignancy from benign in pericardial lesions with 18F-FDG PET/CT
- VernacularTitle:~(18)F-FDG PET/CT鉴别诊断心包良、恶性病变
- Author:
Dan SHAO
;
Shuxia WANG
;
Changhong LIANG
- Publication Type:Journal Article
- Keywords:
Pericardium;
Heart neoplasms;
Tomography,X-ray computed;
Positron-emission tomography;
Diagnosis,differential
- From:
Chinese Journal of Medical Imaging Technology
2010;26(2):333-336
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the feasibility of ~(18)F-FDG PET/CT for differentiation of malignancy from benign in pericardial Lesions. Methods ~(18)F-FDG PET/CT data of 16 patients with pericardial lesions (9 malignancy, 7 benign) were analyzed using maximum standard uptake values (SUV_(max)) and the density of lesions, the relationship with surrounding tissues were also evaluated. The results of malignancy or benign were proved by needle biopsy.Results SUV_(max) of malignancy (10.1±6.0) and benign (3.0±2.1) was significant different (P<0.01). Taking the optimal cut-off value as SUV_(max) 3.5-4.5, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of differentiation of malignant from benign in pericardial lesions was 100%, 85.71%, 93.75%, 90.00% and 100%, respectively. Conclusion ~(18)F-FDG PET/CT can predict benign or malignance of pericardial lesions with moderate accuracy.
