Clinical analysis of polycythemia vera among different nationalities in Xinjiang Uygur Autonomous Region
10.3760/cma.j.issn.1009-9921.2010.01.010
- VernacularTitle:新疆维吾尔自治区不同民族真性红细胞增多症临床分析
- Author:
Yuanyuan WU
;
Minghui DUAN
;
Min MAO
;
Ling FU
- Publication Type:Journal Article
- Keywords:
Polycythemia vera;
XINJIANG;
Uygur nationality;
Han nationality
- From:
Journal of Leukemia & Lymphoma
2010;19(1):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate and compare the clinical feature and natural course of polycythemia vera(PV)between Uygur and Han nationalities in Xinjiang Uygur Autonomous Region.Methods Clinical symptoms,signs,laboratory tests and prognosis of 37(20 Han,13 Uygur,4 other nationalities)patients with PV were analyzed.Results There were 22 males and 15 female.The mean age of all patients was 59.41±11.31(31-85)years old.The mean hemoglobulin level was(191.11±21.41)g/L.Erythremia combined with leukocytosis or thromboeytosis were observed in 23(62.2%)or 19(51.4%)patients respectively.Splenomegaly was found in 27(73.0%)patients and hepatomegaly in 9(24.3%).Serum LDH was elevated in 28(75.7%)patients.Twenty two patients(59.5%)had vascular thrombotic events.Two patients developed MF.N0 secondary neoplasm was identified.Two patients died of thrombosis.Over 60 years old,leukocytosis and thrombocytosis were the high risk factors associated with thrombosis.No significant differences of clinical manifestations and thrombotic events have been found between Uygur and Han patients in Xinjiang.Conclusion Over 60 years old,leukocytosis and thromboeytosis were probably the high risk factors of thrombosis in PV patients.There was no significant differenee in clinical feature and natural course of PV between Uygur and Han nationalities in Xinjiang Uygur Autonomous Region.
