Precursor T-lymphoblastic lymphoma of the breast: one case report and reviews of literature

VernacularTitle:乳腺前体T淋巴母细胞淋巴瘤一例并文献复习
Author: Xiaofan LIU ; Yaozhong ZHAO ; Yafei WANG ; Ying WANG ; Dehui ZOU ; Linsheng QIAN ; Lugui QIU
Publication Type:Journal Article
Keywords: Breast neoplasms; Lymphoma,lymphoblastic
From: Journal of Leukemia & Lymphoma 2008;17(2):110-113
CountryChina
Language:Chinese
Abstract: Objective To improve the recognition of precursor T- lymphoblastic lymphoma (T-LBL)of the breast. Methods One case of breast T- LBL was reported, the development of breast non-Hodgkin lymphoma and T-LBL presenting as breast masses was reviewed. Results One case of breast T-LBL was diagnosed, the patient with a high leukocyte count, breast mass and peripheral lymph nodes was treated with Hyper-CVAD regimen after active therapy and achieved complete remission (CR). Followed by maintenance therapy with Hyper-CVAD regimen for three times, disease free survival had been obtained five month.Conclusion Lymphoma of the brest is a rare malignancy. T-LBL is a highly aggressive disease with adverse prognosis, it is very uncommon for presenting as lymphoma of breast. Initiation of intensive muhiagent chemotherapy can improve the free survival and the prognosis.