Advance of hyaluronon in malignant hematological diseases
10.3760/cma.j.issn.1009-9921.2011.04.022
- VernacularTitle:透明质酸在恶性血液病中作用的研究进展
- Author:
Shuxian CAI
- Publication Type:Journal Article
- Keywords:
Hyaluronic acid;
Hematologic neoplasms
- From:
Journal of Leukemia & Lymphoma
2011;20(4):251-253
- CountryChina
- Language:Chinese
-
Abstract:
The hyaluronon (HA) is an extensive existing non-sulfmucus glycosaminoglycan. The abnormal expression of HA is closely related to the development of malignant hematological diseases. The interation between HA and its receptors, such as CD444, RHAMM, participate in the process of the proliferation,movement, migration, invasiveness and multi-drug resistence in tumors. According to the latest published literatures in recent years, the the studies of HA in tumors, and the functions of HA in the development of malignant hematological diseases are reviewed in this article.
