Evaluation of left ventricular diastolic and systolic function of dogs on different status of acute myocardial ischemia with velocity vector imaging
10.3321/j.issn:1003-3289.2009.12.009
- VernacularTitle:速度向量成像技术评价犬急性心肌缺血状态左心室舒缩功能
- Author:
Chuan ZHANG
;
Daogang ZHA
;
Peng WANG
;
Zhibin XIE
;
Jian LIU
;
Jianping BIN
;
Yili LIU
- Publication Type:Journal Article
- Keywords:
Ventricular function;
left;
Velocity vector imaging
- From:
Chinese Journal of Medical Imaging Technology
2009;25(12):2178-2181
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate left ventricular diastolic and systolic function of the dogs during different status of acute myocardial ischemia with velocity vector imaging (VVI). Methods Six healthy mongrel dogs were enrolled. Home-made artery constrictor was placed in the proximal coronary artery after opening the chest of dogs to produced different grades of coronary artery stenosis. Mean of peak diastolic velocity (Em), peak strain rate of diastole (Esr), mean of peak systolic velocity (Sm), peak strain rate of systole (Ssr), ejection fraction (EF) and left ventricular pressure were measured. Results There was good linear correlation between Em and Esr by VVI and left ventricular end diastolic pressure (LVEDP) (r=-0.834, P<0.001 and r=-0.703, P<0.001, respectively). Em and LVEDP had better correlation than that between Esr and LVEDP (P=0.032). Sm, Ssr or EF had significant correlation with +dp/dt_(max) (r=0.883, P<0.001, r=0.772, P<0.001 and r=0.647, P<0.001, respectively). Significant difference was observed for correlation coefficient between Em and Esr and EF (P<0.001). Conclusion Em and Sm are sensitive echocardiography indexes to evaluate left ventricular diastolic and systolic function, and are better than EF, Esr and Ssr.