A clinical analysis of myelodysplastic syndrome and aplastic anemia combined with autoimmune disease
10.3760/cma.j.issn.1009-9921.2009.01.009
- VernacularTitle:骨髓增生异常综合征与再生障碍性贫血并发自身免痰性疾病的临床分析
- Author:
Xiaoqian XU
;
Jianmin WANG
;
Shuqing Lü
;
Jianmin YANG
;
Li CHEN
;
Xianmin SONG
;
Weiping ZHANG
;
Jun HOU
- Publication Type:Journal Article
- Keywords:
Myelodysplastic syndromes;
Anemia,aplastic;
Autoimmune diseases
- From:
Journal of Leukemia & Lymphoma
2009;18(1):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of pathogenesis and therapeutics of myelodysplastic syndrome(MDS)and aplastic anemia(AA)combined with autoimmune disease(AID).Methods Retrospective analysis and follow-up visit of 111 patients with MDS and 56 patients with AA in our hospital were studied.Results There were 9(8.1%)of 111 patients with MDS and 2 (3.6%)of 55 patients with AA coexistent with AID.Autoimmune hemolytic anemia(36.4%)and Behcet Disease(18.2%)were common among those combined with AID.5 patients had AID proceeding to the occurrence of MDS/AA.4 patients had simultaneous occurrence of AID and MDS/AA.2 patients developed AID three years later after the diagnosis of MDS.Conclusion There was a certain intrinsic relationship between MDS/AA and AID.
