Advance of treatment for newly diagnosed multiple myeloma
10.3760/cma.j.issn.1009-9921.2008.05.031
- VernacularTitle:初发多发性骨髓瘤的治疗进展
- Author:
Xiaowei ZHANG
;
Wenming CHEN
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Therapy
- From:
Journal of Leukemia & Lymphoma
2008;17(5):391-394
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma is a plasma cell malignancy.At diagnosis,most patients are older than 65 years,In newly diagnosed myeloma patients younger than 65 years,high-dose of melphalan followed by autologous stem cell transplantation(ASCT)is regarded as the standard treatment.In elderly patients,usually older than 65 years,oral melphalan and prednisone(MP)has been considered as the standard regimen recently.However,the discovery of thalidomide,lenalidomide,and the proteasome inhibitor bortezomib will increase the effect of clinical treatment.This review will summarize literatures and focus on the treatment of newly diagnosed myeloma.
