Research progress on new agents for follicular lymphoma
10.3760/cma.j.issn.1009-9921.2011.12.020
- VernacularTitle:滤泡性淋巴瘤新药研究进展
- Author:
Shan GAO
- Publication Type:Journal Article
- Keywords:
Lymphoma,follicular;
Lymphoma,non-Hodgkin;
Drug therapy,combination
- From:
Journal of Leukemia & Lymphoma
2011;20(12):762-765
- CountryChina
- Language:Chinese
-
Abstract:
Follicular lymphoma (FL) is a type of B lymphocytic non-Hodgkin lymphoma.Clinically,FL presents with long course,indolent behavior,and is characterized by prompt response to initial therapy but almost invariably subsequent relapses.It is considered incurable with conventional therapies.Appropriate treatment strategies are critical for survival.Recently,several drugs such as rituximab,and bendamustine have been approved for FL treatment.Very promising novel agents like ofatumumab,epratuzumab,lenalidomide,bortezomib and ABT-263 are now under investigation in clinical trials and will provide more choices for FL therapy.