Inhibitor of apoptosis proteins XIAP, survivin and leukemia
10.3760/cma.j.issn.1009-9921.2009.02.020
- VernacularTitle:凋亡抑制蛋白XIAP、Survivin与白血病
- Author:
Yanping ZHANG
;
Taixin SHI
- Publication Type:Journal Article
- Keywords:
Inhibitor of apoptosis proteins;
Leukemia
- From:
Journal of Leukemia & Lymphoma
2009;18(2):117-119
- CountryChina
- Language:Chinese
-
Abstract:
Leukemia is a malignant hyperplasia disease of hematopoietic system. It is characterized that a certain blood cell system proliferates, gets into blood streaming, infiltrates each organism and apparatus and arouse a series of clinical manifestation. In recent years the study of leukemia has discovered that it was correlated with apoptosis of the cells. The roles of XIAP and survivin in apoptosis inhibition have been especially paid attention. It is discovered that they play major roles in the genesis and resistance to chemotherapeutical drug of tumors. We summarize the biological characteristics and the expressions of XIAP and survivin in the children with acute leukemia.
