Outcome Analysis between IVF-ET Cycle and Whole Embryo Freezing and Thawing Cycle in High-Risk OHSS Patients
10.3969/j.issn.0253-9896.2010.03.010
- VernacularTitle:OHSS高危胚胎移植与全胚胎冷冻移植不孕患者结局分析
- Author:
Zhenyu LU
;
Fengqin XU
;
Yunshan ZHANG
;
Ruoran MI
- Publication Type:Journal Article
- Keywords:
embryo transfer;
fertilization in vitro;
ovarian hyperstimulation syndrome;
polycystic ovary syndrome freezing;
cryopreservation
- From:
Tianjin Medical Journal
2010;38(3):189-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effective method to avoid the ovarian hyperstimulation syndrome(OHSS)in infertile patients underwent in vitro fertilization-embryo transfer(IVF-ET)and whole embryo freezing and thawing 2-3 cycles after egg retrieval.Methods:The controlled ovarian hyperstimulation(COH),the number of retrieved oocytes,the number of embryo freezing,and clinical pregnancy rate were compared between 239 patients with the ET cycle(group A)and 164 patients with whole embryo freezing and thawing(group B).Results:The levels of initial dosage of gonadotropins(Gn)and total dosage of Gn were higher in group A compared with those of group B(P < 0.01).The level of estradiol(E2)on day of human chorinonic gonadotrophin(hCG),the number of retrieved oocytes and the number of embryo freezing were lower in group A compared with those of group B(P< 0.01).There were no differences in patient age,COH,rate of OHSS and clinical pregnancy rate between group A and group B.Conclusion:Freezing the whole embryos and thawing ET 2-3 cycles after egg retrieval didn't influence the treatment results in infertile patients.