Epstein-Barr virus infection and development of T-cell lymphoma
10.3760/cma.j.issn.1009-9921.2009.05.022
- VernacularTitle:EB病毒感染与T细胞淋巴瘤的发生
- Author:
Xiaoli XIE
;
Runliang GAN
- Publication Type:Journal Article
- Keywords:
Herpesvinus 4,human;
Lymphoma,T-cell
- From:
Journal of Leukemia & Lymphoma
2009;18(5):312-315
- CountryChina
- Language:Chinese
-
Abstract:
Epstein-Barr virus (EBV) is a kind of DNA tumor virus. Previous Studies on the tumorigenic mechanism of EBV mainly focus on human B lymphocyte. Now there are evidences that EBV exists in human T-cell lymphoma. Exploration in recent years show that EBV could infect T lymphocyte and likely play an important role in the pathogenesis of T-cell lymphoma. Investigation of molecular biological effect of LMP1 in T cell will be helpful for us to understand the approach and mode of EBV infecting T lymphocyte as well as the mechanism of T-cell lymphoma development.
