Study progress of insulin-like growth factor receptor type 1 gene mutation and short stature
10.3760/cma.j.issn.2095-428X.2014.20.004
- VernacularTitle:胰岛素样生长因子-1受体基因变异与矮身材的研究进展
- Author:
Yu YANG
;
Hui HUANG
- Publication Type:Journal Article
- Keywords:
Insulin-like growth factor type 1 receptor;
Short stature;
Growth hormone-insulin-like growth factor axis;
Insulin-like growth factor pathway
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(20):1528-1530
- CountryChina
- Language:Chinese
-
Abstract:
Insulin-like growth factor receptor type 1 (IGF-1 R) is the receptor cascade effect molecules of IGF signaling pathways in the hypothalamus-pituitary-growth hormone axis.In recent years,IGF-1R gene mutation of short stature case reports increased year by year,now the progress of IGF-1R gene defects in short stature for clinicians was summarized.
