Impact of invasive treatment strategy on health-related quality of life six months after non-ST-elevation acute coronary syndrome
10.11909/j.issn.1671-5411.2014.03.003
- Author:
Lixia YANG
;
Yujie ZHOU
;
Zhijian WANG
;
Yueping LI
;
Meng CHAI
- Publication Type:Journal Article
- Keywords:
Non-ST elevation acute coronary syndrome;
Quality of life;
Therapeutic strategy
- From:
Journal of Geriatric Cardiology
2014;(3):206-211
- CountryChina
- Language:Chinese
-
Abstract:
BackgroundFew studies have compared change in the health-related quality of life (HRQL) following treatment of non-ST-elevation acute coronary syndrome (NSTE-ACS) with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). This study is tocompare changes in HRQL six months after hospital discharge between NSTE-ACS pa-tients who underwent either PCI or CABG.Methods HRQL was assessed using the Seattle angina questionnaire at admission and six months after discharge in 1012 consecutive patients with NSTE-ACS. To assess associations of PCI and CABG with HRQL changes, logistic regression models were constructed treating changes in the score of each dimension of the Seattle angina question-naire as dependent variables.Results Although both the PCI and CABG groups experienced angina relief and other improvements at 6-month follow-up (P<0.001), the CABG relative to PCI group showed more significant improvements in angina frequency (P= 0.044) and quality of life (P= 0.028). In multivariable logistic analysis, CABG also was an independent predictor for both im-provement of angina frequency (OR: 1.62, 95%CI: 1.09-4.63,P= 0.042) and quality of life (OR: 2.04, 95%CI: 1.26-6.92,P= 0.038) relative to PCI.Conclusions In patients with NSTE-ACS, both PCI and CABG provide great improvement in disease-specific health status at six months, with that of CABG being more prominent in terms of angina frequency and quality of life.
