Using the technique of amplyfication of nucleic acide arrangement (NASBA) RNA to detect the bacilli of M.leprae in leprosy patient after treatment
- Author:
Vu Tan Trao
- Publication Type:Journal Article
- Keywords:
M.leprae, leprosy
- MeSH:
Mycobacterium leprae;
Leprosy;
RNA
- From:Journal of Practical Medicine
2003;439(1):52-54
- CountryViet Nam
- Language:Vietnamese
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Abstract:
The detection of structural ARN in ribosom-16sr RNA existing in living M.leprae has the value of valuating the efficacy of the treatment and make prognosis of the recurrence . NASBA is performed on 91 samples of biopsy of ear tissue of 2 groups of patients immediately after the treatment of the group I and 5 years after the treatment of the group II. In group I, the positive rate of NASBA is 1/29 and in group II is 3/62. All patients with positive NASBA are in the group of numerous bacilli (MB). In finishing the treatment, there is only 1 patient of MB group who has positive NASBA. Among 60 patients who finishes multichimiotherapy, after 5 years there are 3 patients with positive NASBA
