Advances of vascular endothelial growth factor inhibitors in the treatment of psoriasis
10.3969/j.issn.0253-9896.2015.03.030
- VernacularTitle:血管内皮生长因子抑制剂治疗银屑病的研究进展
- Author:
Junying LI
;
Hong LI
- Publication Type:Journal Article
- Keywords:
psoriasis;
vascular endothelial growth factors;
VEGF inhibitor
- From:
Tianjin Medical Journal
2015;(3):333-336
- CountryChina
- Language:Chinese
-
Abstract:
Psoriasis is a common inflammatory autoimmune disease. Angiogenesis is known to be a key pathogenic fea?ture of psoriasis. The elevation of vascular endothelial growth factor (VEGF) has been demonstrated in the skin and plasma of patients with psoriasis. A number of case reports have indicated that VEGF inhibitor is effective in patients with psoriasis. VEGF inhibitors are consisted of three categories:anti-VEGF monoclonal antibodies, VEGF receptor antagonists and tyro?sine kinase inhibitors. This article reviewed the current clinical application and therapeutic potential of VEGF inhibitors in psoriasis .
