Change of adiponectin levels in patients with different types of atrial fibrillation
10.3969/j.issn.1671-8348.2015.12.018
- VernacularTitle:不同类型房颤患者脂联素的变化
- Author:
Jieqi LI
;
Hong PENG
;
Hongping YANG
;
Rongxian ZHANG
;
Ping LI
;
Quanmin ZHAO
;
Kaibi ZHOU
;
Tianqiong LEI
- Publication Type:Journal Article
- Keywords:
adiponectin;
atrial fibrillation;
natriuretic peptide;
brain;
heart failure
- From:
Chongqing Medicine
2015;44(12):1640-1642
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changeof plasmadiponectin and N-terminal pro-brain natriuretipeptide (NT-proBNP) levelin the patientwith differentypeof atrial fibrillation (Af) .MethodTwo hundred and thirty-fouresearch sub-jectwere divided into 4 group:sinurhythm group (n= 70) ,paroxysmal Af group (n=52) ,permanenAf group (n=62) and control group (n=50) .The plasmadiponectin level wameasured by the enzyme-linked immunosorbenassay (ELISA) and the NT-proBNP level wadetected by chemiluminescence .4 groupwere comparable in age ,gende,body masindex and basidisea-se.ResultThe NT-proBNP level in the paroxysmal Af group and the permanenAf group wasignificantly increased compared with the sinurhythm group and the control group ,the difference wastatistically significan(P<0 .05) ,buthe difference be-tween the sinurhythm group and the control group had no statistical significance (P>0 .05) .The NT-proBNP level in the perma-nenAf group wasignificantly increased compared with the paroxysmal Af group (P<0 .05) .Compared with control group ,the adiponectin level in the sinurhythm group wasignificantly decreased (P<0 .05) ,which in the paroxysmal Af group and the per-manenAf group wasignificantly increased compared with the sinurhythm group and the control group ,the difference wastatis-tically significan(P<0 .05) .The adiponectin level in the permanenAf group wasignificantly increased compared with the parox-ysmal Af group (P<0 .05) .Conclusion The adiponectin level could be related with the repeated occurrence of permanen Af .