Clinical Significance of determination of unconjugated estriol and human placental lactogen in preeclampsia
10.3969/j.issn.1673-4130.2015.13.029
- VernacularTitle:游离雌三醇和人胎盘催乳素测定在子痫前期的意义
- Author:
Xue BAI
;
Yi FAN
- Publication Type:Journal Article
- Keywords:
preeclampsia;
unconjugated estriol;
human placental lactogen;
pregnancy outcome
- From:
International Journal of Laboratory Medicine
2015;(13):1870-1871
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between serum levels of unconjugated estriol (uE3)and human placental lacto-gen (hPL)and preeclampsia.Methods 123 cases of pregnant women diagnosed as preeclampsia were enrolled into observational group,and 1 50 cases of healthy pregnant women were enrolled into control group.Blood specimen were collected from the two groups in 28-<32 gestational weeks and 32-36 gestational weeks.Serum levels of uE3 and hPL were determined and compared between the two groups.Results The pregnancy outcomes of the control group were better than those of the observation group. With the increase of gestational age,there was increasing trend of serum levels of uE3 and hPL in the two groups.However,com-pared with the observation group,the serum levels of uE3 and hPL were higher in the control group,and the differences were statis-tically significant(P <0.05).Conclusion The decrease of serum levels of uE3 and hPL in pregnant women with preeclampsia may be associated with the pregnancy outcomes.
