Analysis of food allergen spectrums in food anaphylaxis in Guangzhou
10.3969/j.issn.1673-4130.2015.13.005
- VernacularTitle:广州地区引起食物过敏性疾病的变应原谱分析?
- Author:
Yun CHEN
;
Huimin WANG
;
Peiyan ZHENG
;
Baoqing SUN
- Publication Type:Journal Article
- Keywords:
food intolerance;
food allergy;
specific IgG antibody;
specific IgE antibody;
distribution characteristics
- From:
International Journal of Laboratory Medicine
2015;(13):1813-1815
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse distribution of age and gender characteristics of specific IgG(sIgG)antibodies and specific IgE (sIgE)antibodies of 13 types of food allergens in patients with food anaphylaxis,and to explore the relationship between sIgG and sIgE in food anaphylaxis.Methods 314 cases of patients from 2009 to 2012 were selected as subjects,and divided into underage group(1 63 cases)and adult group(1 5 1 cases).Serum sIgG of 13 types of food allergens were detected by using enzyme linked immu-nosorbent assay,serum sIgE of these food allergens were detected by using immune capture.Results 80.25% of the patients were sIgG-positive,and no obvious gender differences were found;while the positive rates of sIgG in the underage group(94.48%)were higher than that in the adult group(64.90%),there were statistically significant differences(P < 0.05 ).34.39% of the patients were sIgE-positive.The positive rates of sIgE in male patients(40.68%)were higher than that in female patients(26.28%),and that in the underage group(55.21%)were also higher than that in the adults group(1 1.92%),there were statistically significant differences(P <0.05).Conclusion The total positive rates and its distribution characteristics of sIgG and sIgE of same food aller-gens were obviously different.Food anaphylaxis might be associated with age,gender,food types and individual diversity.
