Oral and maxillofacial appearance of AIDS patients and the detection methods of HIV infection
10.3969/j.issn.1673-4130.2015.13.010
- VernacularTitle:艾滋病的口腔颌面部表现及 HIV 感染检测方法?
- Author:
Bo PANG
;
Feipeng TENG
;
Xiaoyan ZHOU
- Publication Type:Journal Article
- Keywords:
acquired immune deficiency syndrome;
hunman immunodeficiency virus infection;
oral cavity;
maxillofacial re-gion;
clinical feature
- From:
International Journal of Laboratory Medicine
2015;(13):1826-1828
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and analyze the oral and maxillofacial appearance of patients with acquired immune deficiency syndrome(AIDS)and to explore the effective detection methods of hunman immunodeficiency virus(HIV)infection,aimed at early diagnosis of HIV infection and AIDS,providing reference for treatment and prevention.Methods 21 6 cases of suspected HIV infec-tion and AIDS therapy-naive patients in the department of infection disease in this hospital,from January 2012 to March 2014,were selected.Oral and maxillofacial appearances,detection methods and its results were retrospectively analysed.Results The main clinical manifestations of patients with HIV infection and AIDS were oral candidiasis,oral hairy leukoplakia,herpes simplex virus infection,Kaposi′s sarcoma,periodontal disease,ulcer disease and other abnormal attribute.All of the 21 6 samples were positive in the preliminary screening,214 cases were confirmed by western blotting(WB),and the sensitivity,specificity and false positive rate were 99.07%,100.00% and 0.926%,repectively.Conclusion Focusing on clinical symptoms and signs in oral and maxillofacial re-gion of patients with HIV infection and AIDS could provide significant references for clinical diagnosis,and combing detection meth-ods of enzyme linked immunosorbent assay(ELISA)and WB could make a definite diagnosis,which might be benefit to make effec-tive prevention and treatment measures and in order to control the infection and improve the prognosis.
