Changes in plasma levels of D-dimer in patients with prostate hyperplasia complicated with acute urinary retention and its clinical significance

VernacularTitle:前列腺增生伴急性尿潴留患者血浆 D-二聚体水平变化及临床意义?
Author: Yujun FAN ; Jing CAI ; Hui WEI ; Tantan WENG ; Ting YANG
Publication Type:Journal Article
Keywords: prostate hyperplasia; acute urinary retention; D-dimer
From: International Journal of Laboratory Medicine 2015;(13):1833-1834
CountryChina
Language:Chinese
Abstract: Objective To investigate changes in plasma levels of D-dimer in patients with prostate hyperplasia(BPH)complicat-ed with acute urinary retention(AUR),and to explore its clinical significance.Methods 102 cases of patients with prostate hyper-plasia complicated with acute urinary retention,treated in this hospital from July 2013 to December 2014,were selected and divided into the simple BPH group(56 cases)and BPH complicated with AUR(BPH+AUR)group.The plasma levels of D-dimer of these patients were detected and comparatively analysed.Results Compared with the simple BPH group,the plasma levels of D-dimer of patients in the BPH+AUR group was increased,had statistically significant difference.(P <0.01).Conclusion The plasma levels of D-dimer in patients with BPH complicated with AUR increase significantly,which indicates that patients are with secondary in-creased fibrinolytic activity.Measures should be taken to relieve urinary retention as soon as possible,so as to protect the vascular endothelial function of patients and reduce the incidence of complications.