Percutaneous radiofrequency ablation for the treatment of portal vein tumor thrombus：experience of 15 cases
10.3969/j.issn.1008-794X.2014.10.011
- VernacularTitle:经皮穿刺射频消融治疗门静脉癌栓15例
- Author:
Naijian GE
;
Yefa YANG
;
Shuqun SHEN
;
Xiaohe YU
;
Yijun ZHANG
;
Lu WU
;
Jun LIANG
;
Junjun ZHU
;
Shuqun CHENG
;
Feng SHEN
;
Mengchao WU
- Publication Type:Journal Article
- Keywords:
endovascular radiofrequency ablation;
catheter;
percutaneous transhepatic portography;
portal vein tumor thrombus
- From:
Journal of Interventional Radiology
2014;23(10):883-886
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and clinical effect of endovascular radiofrequency ablation (RFA) catheter, the HabibTM VesOpen, in treating portal vein tumor thrombus. Methods Fifteen patients of hepatocellular carcinoma associated with portal vein thrombus causing obstruction of blood flow were enrolled in this study. Guided by ultrasound percutaneous portal catheter implantation was performed, then, under DSA guidance RFA catheter was placed at portal vein tumor thrombus. RF generator (RITA) was connected to the electrodes, the power was set at 10 W for 2 - 10 minutes. The technical success rate, the postoperative complications, the hepatic and renal functions as well as routine blood tests, portal vein blood flow and the ablation extent of portal vein tumor thrombus were evaluated, and the results were analyzed. Results The procedure was successfully accomplished in all patients. No technique-related complications, such as hemorrhage, vessel perforation, bile leak complicated by infection, liver abscess, abdominal bleeding occurred. Direct portography performed immediately after RFA showed that the portal vein was re-opened. Laboratory examinations performed 4 weeks after RFA showed that no obvious changes in hepatic functions and routine blood tests were observed. Doppler ultrasound examinations revealed that flowing blood was obviously displayed within previously obstructed portal vein. CT scanning was carried out in some patients with portal vein thrombus, and it indicated that the portal vein tumor thrombus was reduced in size or even disappeared. Conclusion For the treatment of portal vein tumor thrombus in patients with hepatocellular carcinoma, endovascular radiofrequency ablation is technically feasible, and the initial results indicate that this technique is an effective treatment.
