Risk factors for acute kidney injury after cardiopulmonary bypass operation in children with non cyanotic congenital heart disease
10.11958/j.issn.0253-9896.2015.05.018
- VernacularTitle:儿童非紫绀型先心病体外循环术后急性肾损伤相关危险因素分析
- Author:
Yupeng WEN
;
Cheng CHANG
;
Zhonglun WANG
;
Jie ZHENG
- Publication Type:Journal Article
- Keywords:
extracorporeal circulation;
risk factors;
congenital heart disease;
acute kidney injury;
non cyanotic congenital heart disease
- From:
Tianjin Medical Journal
2015;43(5):515-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence and risk factors of acute kidney injury (AKI) after cardiopulmonary bypass(CRB) in children with non cyanotic congenital heart disease. Methods A total of 150 children who underwent cardiopulmonary bypass operation from 2012 May to 2014 May were analyzed retrospectively. The patients were divided into two groups:AKI group (n=29) and non AKI group (n=121). Clinical data were collected and compared between two groups, including gender, age and baseline serum creatinine level. Multivariate Logistic regression analysis was used to evaluate the risk factors for AKI after operation. Results There was no death in the 150 cases. Comparison between groups, there were significant differences in age, history of heart failure and (or)pneumonia, baseline serum creatinine level, baseline uric acid, body mass, CPB) time, aortic clamping time, mechanical ventilation time, postoperative transfusion and hypotension. Multivariate Logistic regression analysis showed that age (≤1 years old), the history of pneumonia and (or) heart failure, CPB time (＞40 min), aortic clamping time (＞30 min) were the independent risk factors for AKI after operation. Conclusion It is important to choose the best age for surgery in children, actively prevent preoperative complications and shorten the CPB and aorta blocking time for preventing the occurrence of AKI.
