Role of Runx2 in Breast Cancer
10.3969/j.issn.0253-9896.2014.08.030
- VernacularTitle:Runx2在乳腺癌中作用的研究进展
- Author:
Yao TIAN
;
Lu CHEN
;
Bin ZHANG
;
Xuchen CAO
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
DNA-binding proteins;
transcription factors;
receptors,estrogen;
bone neoplasms;
Runx2;
bone metastases;
review
- From:
Tianjin Medical Journal
2014;(8):840-842
- CountryChina
- Language:Chinese
-
Abstract:
Runx2 is a transcription factor belongs to RUNXX family, and it is one of the important factors involved in expression and participation in regulation of mammary specific genes in the mammary gland. The overexpression is also as-sociated with certain characteristics of breast cancer. This article aims to summarize the recent progress of the role that Runx2 plays in breast cancer.
