Antimicrobial resistance rate of Pseudomonas aeruginosa and it’s correla-tion with antimicrobial use density
10.3969/j.issn.1671-9638.2014.11.002
- VernacularTitle:铜绿假单胞菌耐药率与抗菌药物使用强度的相关性研究
- Author:
Hongwei YANG
;
Lili XIANG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
healthcare-associated infection;
antimicrobial agent;
drug resistance,mi-crobial;
rational drug use
- From:
Chinese Journal of Infection Control
2014;(11):646-649
- CountryChina
- Language:Chinese
-
Abstract:
Objective To realize antimicrobial resistance rate of Pseudomonas aeruginosa (P. aeruginosa)and it’s correlation with antimicrobial use density(AUD),and to provide reference for control of healthcare-associated infec-tion.Methods From July 2011 to December 2013,antimicrobial resistance rate of P. aeruginosa isolated from hospi-talized patients and AUD of patients were monitored,and the correlation between them was analyzed.Results AUD of patients decreased from 73.61 in the third and fourth quarters of 2011 to 41.33 in the same quarters of 2013. Corre-lation coefficient of AUD and antimicrobial resistance rate of P. aeruginosa was -0.32~0.88,correlation coeffi-cient of resistance rate of P. aeruginosa to aztreonam and aztreonam use density was 0.88,there was statistical sig-nificance. Conclusion AUD of hospitalized patients revealed a decreasing tendency,suggesting antimicrobial selec-tive resistance should be considered in clinic.
