Research progress of cytokine-induced killer cell-based immunotherapy for malignant lymphoma
10.3760/cma.j.issn.1009-9921.2014.12.017
- VernacularTitle:细胞因子诱导的杀伤细胞治疗恶性淋巴瘤的研究进展
- Author:
Bai HE
- Publication Type:Journal Article
- Keywords:
Malignant lymphoma;
Cytokine-induced killer cell;
Dendritic cell
- From:
Journal of Leukemia & Lymphoma
2014;23(12):760-764
- CountryChina
- Language:Chinese
-
Abstract:
Cytokine-induced killer cells (CIK cells) are a group of CD3+ CD56+ T cell-based heterogeneous cells generated in vitro,with T-cell receptor (TCR) specificity of CD8+ T cells and anti-tumor activity of non-restrictive major histocompatibility complex (MHC).Recent studies indicated that vaccination with CIK cells induced strong anti-tumor activity in the treatment of malignant lymphoma.These researches show that CIK cell-based immunotherapy has the important values for patients with malignant lymphoma.