Correlation between Bile Reflux Gastritis and Helicobacter Pylori Infection in Children
10.3969/j.issn.0253-9896.2014.05.023
- VernacularTitle:儿童胆汁反流性胃炎与幽门螺杆菌感染的关系
- Author:
Yu ZHAO
;
Shuhong ZHANG
;
Fenglin LIU
;
Juan LI
;
Yan LI
- Publication Type:Journal Article
- Keywords:
bile reflux;
gastritis;
helicobacter pylori;
child;
disease classification;
reflux indexing
- From:
Tianjin Medical Journal
2014;(5):485-486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the relationships between bile reflux gastritis (BRG) and Helicobacter pylori infec-tion in children. Methods A total of 258 BRG cases were included in BRG group and 1 749 gastric mucosal inflammation cases without bile reflux were used as control group. Children with BRG were divided into three groups according to the dis-ease classification and they were also sub-divided into three groups according to the bile reflux indexing. The infection rates of Helicobacter pylori were analyzed in different groups. Results Compared to control group (34.02%), the infection rate of Helicobacter pylori was significantly higher in BRG group (46.12%). The infection rates of Helicobacter pylori infection were 40.86%(38/93), 45.53%(56/123) and 59.52%(25/42) in patients with mild, moderate and severe infections. There was no significant difference between them (χ2=4.089, P>0.05). The positive rates of Helicobacter pylori infection were 37.32%(53/142), 53.68%(51/95) and 71.43%(15/21) in children withⅠ,ⅡandⅢreflux indexing, and there was significant differ-ence between them (χ2=12.022,P<0.01). Conclusion Helicobacter pylori infection is one of the causative factors leading to BRG in children. The bile regurgitation increased with the increasing of Helicobacter pylori infection.
