The Peroxiredoxins protein family and related disease
- VernacularTitle:过氧化物还原酶蛋白家族与疾病
- Author:
Ting DUAN
;
Bing YAO
- Publication Type:Journal Article
- Keywords:
Peroxiredoxins;
Oxidative stress;
Reactive oxygen species
- From:
Journal of Medical Postgraduates
2015;(1):98-101
- CountryChina
- Language:Chinese
-
Abstract:
Peroxiredoxins(Prxs) are a family of antioxidant protein that have been identified in prokaryotes and eukaryotes. As antioxidants, Prxs protein contains an active site cysteine that is sensitive to oxidation by H 2 O2, eliminate active oxygen that exist in normal tissues and cells, protect cells from oxidative damage induced by reactive oxygen species ( ROS). Prxs protein is a known free radical scavenger, and has been shown to play a role in several diseases. In this review, recent advances on the study of Prxs protein family and tumor related diseases are reviewed, which is expected to provide new ideas for the diagnosis and treatment of the related clinical diseases.
