MR features of orbital langerhans’cell histiocytosis
10.3969/j.issn.1002-1671.2015.01.006
- VernacularTitle:眼眶朗格汉斯细胞组织细胞增生症的MRI表现特点分析
- Author:
Chunnan WU
;
Hong WANG
;
Pengyu LAN
;
Na YANG
- Publication Type:Journal Article
- Keywords:
orbital;
Langerhans cell histocytosis;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2015;(1):20-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate diagnostic magnetic resonance imaging features of orbital Langerhans cell histocytosis (LCH)and improve its diagnostic accuracy.Methods The symptoms and image data of fourteen histophathology verified orbital LCH cases are reviewed and analyzed.Results Nine patients had swollen eyelids,accompanying with symptoms of inflammation, esphthalmos and orbital masses.One case had cough symptom and another had diabetes insipidus.Of these fourteen cases,seven occurred in right orbital,six occurred in left orbital and one involved bilateral orbital.As to the location of LCH,six cases located in super-lateral wall of the orbit,five cases located in lateral wall of the orbital,and three cases located in roof of orbital.On MRI, thirteen cases lesions show hypo or iso signal intensity on T1 WI,and eleven cases lesions show heterogeneous hyper or iso signal in-tensity on T2 WI.The lesions of eosinophilic granuloma has clear border,which differentiate it from other types.After contrast en-hancement,MR imaging showed marked inhomogeneous enhancement.Conclusion MRI is the primary modality in diagnosing of or-bital LCH,clearly and accurately manifesting the extent of orbital LCH.It will be helpful to diagnose LCH timely if combining with clinical data.MR could provide reliable information for making surgical operation and treatment plan.
