Comparison of lower extremity atherosclerosis between diabetic and non-diabetic patients using dual-source CTA
10.3969/j.issn.1002-1671.2015.01.017
- VernacularTitle:双源CT血管成像对糖尿病与非糖尿病下肢动脉粥样硬化的对照研究
- Author:
Jingang YANG
;
Jialing WU
;
Xiaojun MO
;
Xiang YU
;
Ming GU
- Publication Type:Journal Article
- Keywords:
computed tomography;
atherosclerosis;
diabetes mellitus;
angiography;
lower extremity
- From:
Journal of Practical Radiology
2015;(1):61-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the differences of the lower extremity atherosclerosis between patients with and without type 2 diabetes using dual-source CT angiography.Methods Dual-source CT angiography of lower extremity was performed in 87 patients with (n=30)or without (n= 57 )diabetes.Extent of luminal stenosis,and the type,distribution and range of the plaques were compared.Results 342 plaques in 540 segments (63.3%)in diabetic patients,and 500 plaques in 1 026 segments (48.7%)in non-diabetic ones were detected respectively.Compared with non-diabetic patients,the diabetic ones had a higher overall incidence of plaques (P <0.05).Calcified plaques were the most common in both kinds of patients,and the incidence of mixed plaques was high-er in diabetic patients than that in non-diabetic ones (35.6 % vs.28.4%,P <0.05).Light to moderate stenosis occurred in most diabetic patients,and fewer occlusion was found compared with non-diabetic ones (9.1% vs.1 7.0%,P <0.05).The most common sites of the plaques in diabetic patients were located at distal small arteries below the knee.However,those were located at proximal arteries above the knee for non-diabetic ones.The involvement of atherosclerosis in diabetic patients was more diffused,and the de-gree of Ⅳ (75%-100%)was higher than that in non-diabetic ones (P <0.05).Conclusion Atherosclerosis in lower extremity on dual-source CT angiography is very common in diabetic patients with multi-segmental,diffused,non-obstructive involvement of dis-tal small arteries below the knee.