The relationship between waist circumference and new-onset non-alcoholic fatty liver disease in non-obese patients with diabetes mellitus
10.3969/j.issn.0253-9896.2015.01.020
- VernacularTitle:糖尿病非肥胖人群腰围与新发非酒精性脂肪肝的关系
- Author:
Chunwei YANG
;
Xing LIU
;
Xiurong LIU
;
Xiaotao WANG
;
Jingyi ZHANG
;
Xiuzong YAN
;
Yanru ZHOU
;
Shuohua CHEN
;
Zhengxin CAO
;
Shouling WU
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
cohort studies;
Logistic models;
non-alcoholic fatty liver disease;
waist circumference
- From:
Tianjin Medical Journal
2015;(1):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between waist circumference and new-onset non-alcoholic fatty liver disease in non-obese patients with diabetes mellitus. Methods A total of 1 950 patients with diabetes mellitus, who determined fasting plasma glucose(FPG)≥7.0 mmol/L or who were using hypoglycemic drugs and FPG<7.0 mmol/L,and body mass index (BMI)< 25 kg/m2, was selected in this study using prospective cohort method. Patients were divided into five groups according to the baseline data of waist circumference, including waist circumference<78 cm (A group, n=387), 78 cm90 cm (E group, n=421). Multiple Logistic regression model was used to analyze influential factors of new-onset non-alcoholic fatty liver disease in non-obese patients with diabetes mellitus. Re?sults The average duration of follow-up was(47.24±5.13) months. The incidence rate was 11.85%(231/1 950) in patients with non-alcoholic fatty liver disease. The incidence rates were 6.98%, 9.28%, 12.38%, 14.19%and 15.68%in A, B, C, D and E groups, and which were increased with the increased waist circumference (P<0.05). Results of multiple Logistic re?gression model analysis showed that compared with A group,OR values were 1.97 and 2.19 in D and E groups respectively (P<0.05). Conclusion Waist circumference≥85 cm was the risk factors of new-onset non-alcoholic fatty liver disease in non-obese patients with diabetes mellitus.
