Progress ofβ3-Adrenoceptor Agonists in the Treatment of the Overactive Bladder
10.3969/j.issn.0253-9896.2014.03.029
- VernacularTitle:β-3肾上腺素受体激动剂治疗膀胱过度活动症的研究进展
- Author:
Xiaolin DENG
;
Weihao CHEN
;
Zhichen GUAN
- Publication Type:Journal Article
- Keywords:
β-adrenoceptor agonists;
bladder,overactive;
review
- From:
Tianjin Medical Journal
2014;(3):285-287
- CountryChina
- Language:Chinese
-
Abstract:
The overactive bladder syndrome (OAB) is a prevalent condition among adults. Currently, the present treatment is mainly conservative therapy. Antimuscarinic drugs are currently the first-line treatment for OAB. However, many patients experienced insufficient therapeutic benefit and/or unpleasant side effects. Recent advances in the understand-ing of the physiopathology of OAB have driven a huge amount of basic and clinical research into novel pharmacological com-pounds.β3-adrenoceptor agonists are an emerging drug class for the treatment of the OAB. This study reviewed the pharma-cological profile ofβ3-adrenoceptor agonists and discussed the efficacy, safety and tolerability.
