Value of ~(18)F-FDG PET/CT in detecting primary tumor in patients with bone metastases

VernacularTitle:~(18)F-FDG PET/CT在查找骨转移瘤原发灶中的价值
Author: Ying LIANG ; Ning WU ; Meng LI ; Rong ZHENG ; Ying LIU ; Wenjie ZHANG ; Jing LI ; Ping ZHAO
Publication Type:Journal Article
Keywords: Bone neoplasms; Tomography; emission computed; Tomography; X-ray computed; Fluorodeoxyglucose F18
From: Chinese Journal of Medical Imaging Technology 2009;25(12):2275-2278
CountryChina
Language:Chinese
Abstract: Objective To assess the value of ~(18)F-FDG PET/CT in detecting primary tumors of patients with bone metastases, and to observe PET/CT characteristics of different types of bone metastases. Methods Whole-body ~(18)F-FDG PET/CT images of 34 patients with metastatic bone from unknown primary tumor (CUP) were retrospectively analyzed, and SUVmax was compared in osteolytic and osteoblastic subgroups based on CT characteristics. Results Diagnosis of these patients were confirmed by histopathological findings or ≥3 months follow-up. Primary tumors were detected with PET/CT in 22 patients (64.71%). SUV_(max) was 6.78±3.66 in 23 osteolytic metastases, and 4.13±1.69 in 11 osteoblastic metastases (P＜0.05). Conclusion ~(18)F-FDG PET/CT is helpful to find the localization of unknown primary tumors in patients with bone metastases, and to make treatment Planning. Osteolytic metastases show higher metabolic activity on ~(18)F-FDG PET/CT.