Progress of t (14;18) transiocation and c-myc gene rearrangement in diffuse large B-cell lymphoma
10.3760/cma.j.issn.1009-9921.2009.10.018
- VernacularTitle:弥漫性大B细胞淋巴瘤t(14;18)易位和c-myc基因重排研究进展
- Author:
Hongwei ZHANG
;
Niuliang CHENG
- Publication Type:Journal Article
- Keywords:
Lymphoma,non-Hodgkin;
Lymphoma,diffuse;
Rearrangement,gene;
Research
- From:
Journal of Leukemia & Lymphoma
2009;18(10):630-633
- CountryChina
- Language:Chinese
-
Abstract:
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of tumors composed of large B cells. It is the most common type of non-Hodgkin lymphoma. As its variety of clinical, morphological and genetic characters, the classification and prognosis are still debated. This article aims to elucidate t(14;18) translocation and c-myc gene rearrangement is of great significance to the clinical diagnosis, classification, treatment and prognosis of DLBCL.
