Diagnostic value of ~(18)F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules
- VernacularTitle:~(18)F-FDG PET/CT结合胸部屏气螺旋CT对肺结节的诊断价值
- Author:
Ying LIU
;
Ning WU
;
Rong ZHENG
;
Ying LIANG
;
Wenjie ZHANG
;
Meng LI
;
Ping ZHAO
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Neoplasm staging;
Tomography,emission-computed;
Tomography,X-ray computed;
Fluorodeoxyglucose F18;
Standardized uptake value;
Diagnosis,differential
- From:
Chinese Journal of Medical Imaging Technology
2010;26(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the diagnostic value of ~(18)F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules. Methods One hundred and fifty-four patients with 171 pulmonary nodules (≤3 cm) were studied. Each patient underwent ~(18)F-FDG PET/CT (16 slices) examination during mild respiration and breath-hold spiral CT scan, while 123 patients underwent dual-time-point PET/CT examination. The diagnostic efficacy of ~(18)F-FDG PET/CT combined with breath-hold spiral CT,~(18)F-FDG PET/CT, breath-hold spiral CT and taking SUV_(max)≥2.50 as the threshold value for malignancy were compared. All results were proved by pathologically, or by diagnostic therapy or by clinical follow-up. Results The SUV_(max routine) was 4.51±3.06 in 118 malignant nodules, and 2.07±1.30 in 53 benign nodules. The sensitivity, specificity, accuracy and Youdenindex of ~(18)F-FDG PET/CT combined with breath-hold spiral CT was 95.80%, 81.10%, 91.20%and 0.77, respectively, higher than those of other three methods. Conclusion ~(18)F-FDG PET/CT combined with breath-hold spiral CT has high diagnostic value in the differentiation of pulmonary nodules.
