A Case of a Solid and Papillary Epithelial Neoplasm of the Pancreas with Local Invasion into the Duodenum.
- Author:
Hyung Ju KIM
1
;
Soong LEE
;
Soo In CHOI
;
Sang Hoo PARK
;
Sang Kuk KIM
;
Seong Won YANG
;
Jeong Pyeong SEO
;
Hong Bae PARK
;
Young Kyu PARK
;
Jong Jae JUNG
Author Information
1. Department of Internal Medicine, College of Medicine, University of Seonam, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
Solid and papillary epithelial neoplasm of the pancreas
- MeSH:
Abdominal Pain;
Cholangiopancreatography, Endoscopic Retrograde;
Connective Tissue;
Duodenum*;
Female;
Humans;
Immunohistochemistry;
Necrosis;
Neoplasm Metastasis;
Neoplasms, Glandular and Epithelial*;
Pancreas*;
Pancreaticoduodenectomy;
Phosphopyruvate Hydratase;
Prognosis;
Pylorus;
Young Adult
- From:Korean Journal of Gastrointestinal Endoscopy
1999;19(6):983-989
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A solid and papillary epithelial neoplasm of the pancreas is a very rare and low-grade type of malignancy, although an increasing number of cases have been reported in recent years. Patients with a solid and papillary epithelial neoplasm of the pancreas have a good prognosis and may be cured if the disease is diagnosed before metastasis and diffuse local invasion. A 23-year-old female who had a 4-year history of recurrent abdominal pain, was admitted due to lower abdominal pain. Incidentally a calcified, 6 4 cm sized ovoid mass was found in the right upper quadrant, from a simple abdominal X-ray. An ERCP, abdominal sonography, and CT were performed, as well as a pylorus preserving pancreatoduodenectomy. Gross pathologic examination revealed a well encapsulated mass with cystic degeneration and hemorrhagic necrosis. Microscopically, the tumor had papillary fronds with a fibrovascular connective tissue core. There was focal infiltration of tumor cells into the duodenal wall and heterotropic pancreatic tissue in the submucosa. Immunohistochemistry revealed positivity for neuron-specific enolase. The patient maintained a healthy status for one year since the operation.