Experimental Research of Acupuncture at Zusanli(ST 36)for Anti-aging

VernacularTitle:Experimental Research of Acupuncture at Zusanli(ST 36)for Anti-aging
Author: Yicong XIE ; Fang TANG ; Xuejun CUI
Publication Type:Journal Article
Keywords: Aupuncture Therapy; Superoxide Dismutase; Malondialdehyde; Aging; Points,Zusanli (ST 36); Mice
From: Journal of Acupuncture and Tuina Science 2008;6(6):334-336
CountryChina
Language:Chinese
Abstract: Objective: To explore the mechanism of anti-aging effect of acupuncture at Zusanli (ST 36). Methods: Thirty mice of 28 weeks old were randomly divided into 3 groups: control group, model group and acupuncture group. Sub-acute aging model was established by subcutaneous injection of D-galactose. The activity of Superoxide Dismutase(SOD) and content of serum Malondialdehyde(MDA) were measured. Morphological changes of jejunal mucosa were observed with light microscope. Result: SOD activity in the acupuncture group was highest among the three groups, whereas, MDA content was the lowest. In the model group, the ratio of normal intestinal villus was decreased, the intestinal villus was shrunk, and there were more epithelial cells desquamated. In acupuncture group, there were less abnormal intestinal villus and epithelial cell. Conclusion: Acupuncture at Zusanli (ST 36) has an effect in resisting aging by increasing the activity of serum SOD, decreasing the MDA contents, and improving the intestinal villus.