Quantitative analysis of kidney on 3.0T 1H-MRS
10.3321/j.issn:1003-3289.2009.07.036
- VernacularTitle:肾脏3.0T单体素1H-MRS定量观察
- Author:
Kaiming CAO
;
Nanxin HAO
;
Wei WANG
;
Shixin CHANG
;
Yibin WANG
;
Genlin ZONG
- Publication Type:Journal Article
- Keywords:
Magnetic resonance spectroscopy;
Carcinoma,renal cell;
Quantitative analysis
- From:
Chinese Journal of Medical Imaging Technology
2009;25(7):1248-1250
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze proton MR spectroscopy (1H-MRS) characteristics of kidney in vivo, and to investigate the changes and applications of metabolites of kidney on 3.0T MR. Methods Fifteen patients with renal cell carcinoma and 50 healthy volunteers underwent single-voxel PRESS sequence MR scan on 3.0T scanner. Results Satisfied spectra of 13 patients and 48 volunteers were obtained. There were four main groups resonance peak: cholesterol and the unsaturated parts of the olefinic region of fatty acids (Chol+Unsat), water, choline metabolites (Cho) and lipids (Lip). The ratio of the Chol+Unsat to Lip was 5-fold lower in renal cell carcinomas group than that in contrast group (F=4.764, P=0.04). Conclusion A number of chemical compounds pertaining to metabolism in kidney can be quantitative analyzed, which may offer assistance for diagnosis of renal cell carcinoma.
