Advances in treatment of elderly patients with acute myeloid leukemia
10.3760/cma.j.issn.1009-9921.2010.09.021
- VernacularTitle:老年急性髓系白血病治疗进展
- Author:
Tianjiao ZHANG
- Publication Type:Journal Article
- Keywords:
Acute myeloid leukemia;
Aged;
Therapy
- From:
Journal of Leukemia & Lymphoma
2010;19(9):573-576
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemias (AML) in elderly patients showed less well response to therapy as well as relative poor prognosis, due to features of both host and disease biology in the elder. During the past decade, treatments for elderly AML have yielded some advances, including improvements in conventional chemotherapy, application of novel chemotherapeutic agents, immunotherapy approaches, and investigation of epigenetic drugs and targeted therapies, to which some subgroups in clinical trials have showed better response. These advances in current treatments of elderly AML will be reviewed.
