Dementia Following Infarcts in the Left Tuberothalamic Territory:Review of Six Patients.
- Author:
Kyoung HEO
1
;
Byung In LEE
;
Kyoon HUH
;
jin Soo KIM
;
Seung Min KIM
;
Myung Sik LEE
;
Byung Chul LEE
Author Information
1. Department of Neurology, College of Medicine, Yonsei University.
- Publication Type:Original Article
- MeSH:
Cognition;
Dementia*;
Humans;
Memory;
Neuroimaging;
Thalamus
- From:Journal of the Korean Neurological Association
1989;7(2):188-198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Modern capacity for high-resolution brain imaging has facilitated studying the clinicoanatomic correlations of small lesions in subcortical nuclear structures. Several recent reports have convincingly demonstrated that there were particular clinical syndromes associated with specific distributions of thalamic lesions. Thalamic dysfunction due to diveres casues, particularily in the left side has been associated with memory impairment, speech disturbance, cognitive deficits, and behavioural changes. Simplified bedside behavioral examinations were performed in six patients with the left tuberothalamic infarcts. We found severe neuropsychological deficits considered as dementia meeting the DSM III criteria, leaving few focal motor and sensory deficits. The disturbance of attention, speech, cognition and behavior after the left tuberothalamic infarcts are probably related not only to intrinsic thalamic dysfunction itself, but also to the disruption of the regular function of motor, sensory, and integrative cortical stuctures connecting with the thalamus.
