Analysis of the distribution characteristics and drug sensitivity of nosocomial infection in patient with hematologic neoplasms

VernacularTitle:血液肿瘤患者化疗后院内血行感染细菌分布特点及药敏分析
Author: Haiyan LENG ; Lan BO ; Zi CHEN ; Fuqi AI ; Yanhui XIE ; Peiyi RUAN ; Xiaoping XU
Publication Type:Journal Article
Keywords: Hematologic neoplasms; Bacterial infection; Blood; Drug sensitivity
From: Journal of Leukemia & Lymphoma 2009;18(2):90-92
CountryChina
Language:Chinese
Abstract: Objective To investigate clinical distribution and drug sensitivity of infectious pathogens in our wards for hematology malignancies. Methods Drug sensitivity tests of bacteria were performed by Kirby-Bauer method, 56 strains of pathogens were isolated from all detected samples. Results The results showed that the composition ratio of Gram-negtive bacteria, Gram-positive bacteria was 69.64%, 30.36%. In decreasing frequency, Escherichia coli (37.50%), Klebsiella pneumoniae (10.71%). All of staphylococcies were resistant to meticillin, and sensitive to vancomycin. Conclusion This study indicates that Gramnegative bacteria remain the predominant pathogens in microorganisms causing bloodstream infections for hematological malignancies at Huashan Hospital. The incidence of Escherichia coli is the highest. All of staphylococcies were resistant to meticillin.