Effect of MINE-ESHAP regimen in treatment of refractory or relapsed non-Hodgkin lymphoma

VernacularTitle:MINE-ESHAP联合方案治疗难治或复发性非霍奇金淋巴瘤28例
Author: Guoan FENG ; Zhengyun XING
Publication Type:Journal Article
Keywords: Lymphoma,non-Hodgkin; Antineoplastic combined chemotherapy protocols; Outcome
From: Journal of Leukemia & Lymphoma 2010;19(6):363-364
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy of MINE-ESHAP regimen in treatment of refractory and relapsed non-Hodgkin lymphoma (NHL). Methods Twenty-eight patients with refractory and relapsed NHL were treated with MINE-ESHAP regimen. Results The rate of complete remission was 39.3 %(11/28),of partial remission 21.4 %(6/28),of stable disease 17.9 %(5/28),and of progression 17.94 %(5/28). The midsurvival time was 28.5 months. One patient died of infection during marrow restrain period. The main toxicities included gastrointestinal symptoms and myelosuppression. Conclusion MINE-ESHAP regimen is sate and could be employed in treatment of the patients with refractory and relapsed NHL.