Clinical Study on Acupuncture in Treating Diarrhea-predominant Irritable Bowel Syndrome
10.1007/s11726-008-0360-1
- VernacularTitle:Clinical Study on Acupuncture in Treating Diarrhea-predominant Irritable Bowel Syndrome
- Author:
Huirong LIU
;
Yun YANG
;
Huangan WU
;
Yuanchun XIAO
- Publication Type:Journal Article
- Keywords:
Acupuncture-Moxibustion Therapy;
Indirect Moxibustion;
Irritable Bowel Syndrome;
Serotonin;
5-HT
- From:
Journal of Acupuncture and Tuina Science
2008;6(6):360-362
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the changes of 5-hydroxytryptamine (5-HT) in colonic membrane of diarrhea-predominant irritable bowel syndrome (IBS-D) and the clinical efficacy of herbal cake-partitioned moxibustion in treating it, and to explore the action mechanisms. Methods: Seventy-three subjects were randomized into two groups: moxibustion group in which 37 cases were treated by herbal cake-partitioned moxibustion and needling group in which 36 cases were treated by needling. The clinical efficacy and 5-HT expression in colonic membrane were observed. Results: The cure rate was 43.2% in the moxibustion group and 36.1% in the needling group, with no significant difference between the two groups (P>0.05). Herbal cake-partitioned moxibustion could reduce 5-HT expression in colonic membrane. Conclusion: Herbal cake-partitioned moxibustion might improve the clinical symptoms of IBS-D by reducing 5-HT expression.