Application of mesenchymal stem cells in hematopoietic stem cell transplantation
10.3760/cma.j.issn.1009-9921.2011.07.019
- VernacularTitle:间充质干细胞在造血干细胞移植中的应用
- Author:
Hao ZHANG
;
Jun MA
- Publication Type:Journal Article
- Keywords:
Mesenchymal stem cells;
Graft vs host disease;
Hematopoietic stem cell transplantation;
Immunoregulatory function
- From:
Journal of Leukemia & Lymphoma
2011;20(7):433-435
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSC) are non-hematopoietic, multipotent progenitor cells which can be isolated from various human adult tissues. In recent years, MSC have been shown to possess broad immunoregulatory function and tissue regeneration. This review discusses mesenchymal stem cells in hematopoietic stem cell transplantation, including disorders as diverse as acute and chronic graft-versus-host disease, graft failure, pure red cell aplasia, autoimmune thrombocytopenic purpura, hemorrhagic cystitis.
