The relationship between lymphoma after auto-bone marrow transplantation and autoimmune disease
10.3760/cma.j.issn.1009-9921.2008.04.014
- VernacularTitle:自体骨髓移植治疗淋巴瘤合并自身免疫性疾病的探讨
- Author:
Juan HE
;
Ming ZHAI
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Arthritis,rheumatoid;
Bone marrow transplantation
- From:
Journal of Leukemia & Lymphoma
2008;17(4):281-283
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate therapeutic effect,safety and post transplant immunological reconstitution for patients of lymphoma after autologous bone marrow transplantation and occurrence of Rheumatoid Arthritis.Methods The clinical situation,laboratory index and immunological reconstitution was observed for patients of lymphoma after inductive treatment,BCEA of pretreatment,autologous bone marrow transfusion,G-CSF and radiotherapy to lymph node.Results Recovery of hemopoiesis was observed after 28 days.Disappearance of joint swelling and negative ESR,CRP,IgMRF were observed after 2 months.The patients started to work after 3 months. No recurrence of lymphoma and Rheumatoid Arthritis has been observed until today.Conclusion The autologous bone marrow transplantation was safe and effective for the treatment to patient of lymphoma with rheumatoid arthritis,which was a new method for the treatment to lymphoma and other autoallergic diseases.
