Systematic Review of Effects of Nasal Continuous Positive Airway Pressure on Apnea of Preterm Infants.
- Author:
Eun Joo KIM
1
Author Information
1. Department of Nursing, Sangji University, Wonju, Korea. kimeju0409@sangji.ac.kr
- Publication Type:Meta-Analysis ; Original Article
- Keywords:
Review;
Continuous Positive Airway Pressure;
Apnea;
Infant;
Premature
- MeSH:
Apnea*;
Continuous Positive Airway Pressure*;
Humans;
Infant;
Infant, Newborn;
Infant, Premature*;
Odds Ratio;
Ventilator Weaning;
Ventilators, Mechanical
- From:Child Health Nursing Research
2014;20(3):225-235
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to analysis the effects of nasal Continuous Postive Airway Pressure (nCPAP) for preterm infants using systematic review and meta-analysis. METHODS: Thirteen peer-reviewed journals including preterm infants and apnea and nCPAP published between 1973 and 2013 were included. Effect size and statistics of homogeneity were done using STATA 10.0. RESULTS: The design for 9 studies was Randomized Control Trial. In most of studies the pressure of nCPAP was set to 4-6 cmH2O. The effect size of 5 studies for the effect on apnea rate using nCPAP compared to nasal Intermittent Positive Pressure Ventilator (nIPPV) showed that the Standardized Mean Difference (SMD) was -0.11 and was not significantly different (Z=0.41, p=.680). But the difference in nCPAP for nasal Synchronizes Intermittent Positive Pressure Ventilator (nSIPPV) (subgroup) was significant (SMD=-.44). The effect size of 7 studies on effect for ventilator weaning of using nCPAP compared to nIPPV showed the Risk Ratio (RR) as 1.60 and was not significantly different (Z=1.12, p=.268). But the difference between nCPAP and nSIPPV (subgroup) was significant (RR=3.94). CONCLUSION: The results indicate a need for an advanced care system and suggest continuous studies of apnea in preterm infants.
