The Predictive Value of MELD-Na, MELD and Child-Pugh Scoring System for Liver Failure with Artificial Liver Support
10.3969/j.issn.0253-9896.2009.07.007
- VernacularTitle:MELD-Na、MELD及Child-Pugh评分系统预测人工肝治疗的肝衰竭预后价值的探讨
- Author:
Yanying GAO
;
Tao HAN
;
Zhiehan KAN
- Publication Type:Journal Article
- Keywords:
liver,artificial;
liver failure;
prognosis;
injury severity score;
ROC curve
- From:
Tianjin Medical Journal
2009;37(7):547-549
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the value of MELD-Na scoring system, MELD scoring system and Child-Pugh scoring system for liver failure with artificial liver support. Methods: The values of MELD-Na scoring system, MELD scoring system and Child-Pngh scoring system were evaluated using receiver operating characteristic (ROC) curves. Results: The area under curve (AUC) values generated by the ROC curves for Child-Pugh score were higher (AUC=0.794) than those of ME LD-Na score (AUC=0.724) and MELD score (AUC=0.664) respectively. The eutoff scores of three systems were 10.5, 24.8, 26.4 respectively, which could discriminate higher and lower mortality accurately. There were no significant statistic differences in predictive values of three systems for different liver failure(sub-acute liver failure and chronic-on-acute liver failure). But the Child-Pugh scoring system was the best for prediction of the chronic liver failure. Conclusion: MELD-Na scoring system,Child-Pugh scoring system and MELD scoring system can predict the prognosis of liver failure, in which the Child-Pugh scoring system was the best.
