Angiopoietins and their receptor Tie-2 in hematopoiesis and hematologic malignancies
10.3760/cma.j.issn.1009-9921.2009.04.024
- VernacularTitle:血管新生素家族及其受体Tie-2与正常造血及血液肿瘤
- Author:
Yan LI
;
Yingchang MI
- Publication Type:Journal Article
- Keywords:
Vaseular endothelial growth factor A;
Hematologic neoplasms;
Prognosis
- From:
Journal of Leukemia & Lymphoma
2009;18(4):246-249
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis plays an important role in solid tumors and hematologic malignancies. Angiopoietins act as essential regulators in this process,complementary with another mediator-VEGF. In the development of hematologic malignancies, the expression of Angs/Tie-2 system is identified abnormal, especially for Ang-2, whose expression and prognostic impact have gained significant attention recently.
