COX-2 and leukemia
10.3760/cma.j.issn.1009-9921.2009.02.019
- VernacularTitle:环氧合酶-2与白血病
- Author:
Ruicang WANG
;
Hongling HAO
- Publication Type:Journal Article
- Keywords:
Cyclooxygenase-2;
Cyclooxygenase-2 inhibitors;
Leukemia
- From:
Journal of Leukemia & Lymphoma
2009;18(2):115-117
- CountryChina
- Language:Chinese
-
Abstract:
Cyclooxygenase-2 (COX-2) is the rate-limiting enzyme in the production of arachidonic acid to PG, and was differently expressed in leukemia, which may be involved in the progression of leukemia. The specific COX-2 inhibitor might become a new target for the therapy of leukemia. In this article, the effect of COX-2 in pathogenesy of leukemia and application of COX-2 inhibitor in leukemia are reviewed.
