The Role of related apoptosis gene in the pathogenesis of multiple myeloma
10.3760/cma.j.issn.1009-9921.2010.08.020
- VernacularTitle:相关凋亡基因在多发性骨髓瘤发病中作用的研究进展
- Author:
Qiuping BAO
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Apoptosis;
Survivin;
Smac;
Research
- From:
Journal of Leukemia & Lymphoma
2010;19(8):509-512
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma (MM) is a clonal plasma cell malignancy, a low proliferative and low apoptotic activity molecular cloning of a disease, which indicates that apoptosis inhibition may play an important role in the pathogenesis of MM. Therefore, the study of MM pathogenesis-related promoting apoptosis genes/proteins and inhibiting of apoptosis genes/proteins, as well as the correlation between them provides a new strategy for molecular targeted therapy.
